Fabry Disease Treatment Market Highlights:
Fabry Disease Market Size was valued at USD 2.1 billion in 2022 and is projected to grow from USD 2.26 Billion in 2023 to USD 4.12 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.8% during the forecast period (2023 - 2032).
Technological advancements, strong pipeline, advancements in healthcare facilities, and favourable funding policies are expected to drive the market growth over the forecast period. Owing to the increasing awareness about Fabry disease market new and existing market players are coming up with better treatment approaches. For instance, in 2018, 2018, Amicus Therapeutics launched Gala fold capsules 123mg for the treatment of patients aged 16 years and older with a confirmed diagnosis of Fabry disease and who have an amenable mutation.
The market is segmented into enzyme replacement therapy, chaperone therapy, and substrate reduction therapy. Enzyme replacement therapy is expected to remain the most commonly used treatment option for Fabry disease during the forecast period due to its effectiveness in reducing symptoms and improving quality of life.
The COVID-19 pandemic has had a substantial influence on the market for Fabry disease treatment. The pandemic has led to disruptions in supply chains and manufacturing processes, leading to shortages of essential drugs used in treating Fabry disease. However, with the ongoing vaccination drive and relaxation of restrictions worldwide, it is expected that the market will recover soon.
However, diverse range of symptoms, and related complications can restrain the market growth over the assessment period.
Regional Analysis:
Geographically, the Americas is expected to dominate the global market owing to the increasing technological advancements and rising research and development activities. Gastrointestinal manifestations such as abdominal pain, diarrhoea and nausea are significant burden in a patient with Fabry disease. So, for the advanced treatment of these patients Smart Pill testing procedure is developed to gain additional understanding of Fabry disease manifestation via motility abnormalities to improve symptom targeted therapy. This device is currently under clinical trial and the sponsor of this study is Massachusetts General Hospital.
Europe is expected to hold the second largest market share. Nearly 2.2 in 10,000 people in the European Union (EU) are affected with Fabry disease and Fabrazyme (agalsidase beta), Galafold (migalastat) and Replagal (agalsidase alfa) are the three authorized drugs used for the treatment of Fabry disease.
Asia-Pacific is expected to be the fastest growing market owing to the improving healthcare infrastructure.
Moreover, the Middle East and Africa region is expected to hold the least market share in the global Fabry disease market.
Fabry Disease Market Players
The global Fabry disease market research players are Amgen Inc., Amicus Therapeutics, Inc., AVROBIO, Inc., Idorsia Pharmaceuticals Ltd, Protalix, Bristol-Myers Squibb Company, GlaxoSmithKline, iBio, Inc., Neuraltus Pharmaceuticals, Inc., Novartis AG, Pfizer Inc., Sanofi, Shire, Takeda Pharmaceutical Company Limited, Teva Pharmaceutical Industries Ltd and others.
Segmentation:
The Global Fabry Disease Market has been segmented into type, diagnosis & treatment, and end user.
The market, based on type, has been segmented into type-1 and type-2. The type-2 Fabry disease holds the major Fabry Disease Market share due to the high occurrence of type-2 Fabry disease i.e., 1 in 1,500 to 4000 males.
The market, by diagnosis & treatment, has been segmented into diagnosis and treatment. The diagnosis segment is further classified as blood test, urine test, thyroid test, lung function test, and imaging. The imaging segment includes electrocardiogram (EKG), echocardiogram, brain MRI, CT scan and others.
The treatment segment is further classified as enzyme replacement therapy, gene therapy, pharmaceutical formulations containing glissade alfa, analgesics, anticonvulsants, nonsteroidal anti-inflammatory drugs (NSAIDs), and others.
The market, by end user, has been segmented into hospitals & clinics, diagnostic centres, research & academic institutes, and others.
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