Derrick Henry and Christian McCaffrey both warrant considerations as the No. 1 overall pick in standard-league fantasy football drafts. In PPR, of course, McCaffrey easily edges Henry (though Dalvin Cook and Alvin Kamara are also in the mix). McCaffrey finished '19 as the top dog in standard, while Henry sat comfortably at the top in '20. While they're both top-tier options, they earn their living in very different ways, and fantasy owners might be having a tough time figuring out who Jeff Bagwell Jersey should top the RB rankings on their cheat sheets in 2021.Below, we'll compare the two (plus Kamara and Cook) and explain what might set them apart from the pack. It's splitting hairs here,but when you're on the clock with the No. 1 pick, you'llhave to make the crucial decision.DOMINATE YOUR DRAFT:Who Should Be The No. 1 Overall Pick In Fantasy Drafts:Christian McCaffrey or Derrick Henry?The case for McCaffreyIn 2019, McCaffrey was RB1 acro s standard and PPR formats, netting the (471.2 fantasy points). Four. Seven. One.In standard leagues, he produced 355.2 points, nearly four fantasy points per game (FPPG)ahead of No. 2, Derrick Henry. He's a hybrid running back/receiver, and he's been ashoo-in for 20-plus touches a game. The efficiency will be there, but even when it's not, Carolina stillfeeds him the rock. In '19 he accumulated 403 touches (25.19 per game) for north of 2,300 yards from scrimmage.2021 STANDARD FANTASY RANKINGS: | | | | | | Sam Darnold is under center for the Panthers this year. What do we equate with Sam Darnold? Bad quarterback play. What helps bad quarterbacks get easy completions? Running back targets. McCaffrey is not only an elite dump-off target, but he's also a true focal point in the pa sing offense, with plays drawn up specifically Mike Scott Jersey for him on a regular basis.2021 PPR FANTASY RANKINGS:||||||The case against McCaffreyLast season, McCaffrey dealt with high-ankle, shoulder, and glute strains, limiting him to just three games. Is this a sign the Panthers may pull back the reigns on his touches a bit? It surely seems so, particularly in the early part of the season. Also, the Panthers now have a solid WR corps, which should mean more open receivers. As a domino effect, the dump-down frequency may see a slight dip.MORE 2021 FANTASY HELP: | | | Carolina also made sure to addre s the backup running back situation after the departure of Mike Davis. In the fourth round of the 2021 NFL Draft, they selected highly productive college RBChuba Hubbard out of Oklahoma State. No, we're not insinuating Hubbard is anywhere close to a threat to CMC's job, but perhaps Carolina plans to spell him a little bit more, saving some of his bumps and bruises. It would be a smart move to start McCaffrey off with a smaller workload, letting him acclimate back after an injury-riddled season. Even if that's the case, he's still an elite option at the position. In 2021, we might see more games with borderline 20 touches, as opposed to knocking on the door of 30.2021 FANTASY SLEEPERS Jake Marisnick Jersey :|||||The case for HenryIs there any running back in the NFL you can reasonably say has more an effect on winning than Henry? You'd be hard-pre sed to make a case. Put simply, he has a command over the carries like no other back in the NFL. Despite having a lackluster number of targets last year (31 -- 38th among running backs), Henry ranked fourth among running backs in opportunity share (percentage of ateam's total running back carries plus targets), via .2021 FANTASY AUCTION VALUES (Standard PPR):||||||He's going to get the ball early and often (378 carries in '20).One of the best things about Henry is he heats up when it matters most for your fantasy team. In September he averaged a mere 3.9 yards/carry. As we approach the colder months, with the defenses getting worn down, he elevates his game. In December, he was netting 5.9yards/carry. This has been a common theme over the course of his career and certainly was during his 2,000-yard rushing season.Lastly, he doesn't carry the same injury history around with him as the premier backs in the league. ThinkMcCaffrey, Dalvin Cook, Saquon Barkley. He's mi sed a grand total of one game since he became the full-time starter in Tenne see.2021 FANTASY TIERS DRAFT STRATEGY:||||The case against HenryThe obvious negative for Henry is his lack of receiving skills and opportunities Robinson Chirinos Jersey . Yes, we're not discu sing PPR here (for the record, we have him ranked fifth overall in ), but his non-existent receiving role leaves extra yards on the table. If he had a strong receiving acumen, he'd be the easy choice for No. 1 acro s all formats. He must have a significant grip of the rushing titleand continue to sit near the top of the rushing touchdown list to claim the No. 1 nod once again. It's not that he can't do it, but he has to continue to play at the highest level in order to pull it off. Can he really continue that, and when will the injury demonfinally reveal itsugly head after 681 carries the past two seasons?2021 FANTASY CONSISTENCY RATINGS: | | | The VerdictAs our rankings show, we give Henry the nod as the . Yes, the case against Henry presents some obstacles and worries about his future fantasy prospects, but how can we a sume he'll slow down or get injured if we haven't seen it?Remember, although Henry has seen a huge workload in the past two seasons, he's only been the clear-cut workhorse in the offense for justthose two seasons.He entered the league at the same time as Ezekiel Elliott,yet has 396 fewer career touches (about a whole season's worth). It's not quite time for him to be run into the ground. Also, he's 6-3, 247 pounds. That kind of size can take more of a pounding.With McCaffrey's injury concern and size (5-11, 205 pounds), he might not seequiteas much work as his unbelievable 2019. Henry's workload has zero doubts. There's not a Houston Astros Jersey scenario in which another TitansRB will eat into any significant amount of carries. Can we confidentlysay the same about McCaffrey coming off an injury-plagued season? In PPR, McCaffrey takes the crown. For our money, roll with King Henry in standard.FANTASY DRAFT STRATEGY:|||Are any other RBs worthy of the No. 1 overall pick?Dalvin CookCook is certainly a consideration for the No. 1 pick,but his inability to stay on the field has kept him out of the No. 1 spot in the past. Over the course of his four-year career, he's mi sed 21 of 64 po sible games. To be fair, he's mi sed just four games total the past two years, but between the injury worries and the relatively mediocre receiving totals (44 catches last year),