Key Market Insights
§ Presently, close to 50 gene switch platforms are being developed for various applications in adoptive cell therapies (ACT), including CAR-Ts, TCRs and gene therapies; majority of them are protein-based gene switches
§ Various small molecules, including rimiducid, rapamycin and dasatinib, are being investigated to design safety switch for ACTs; management of treatment related toxicity has emerged as the key application of such platforms
§ The current market landscape is fragmented, featuring the presence of both new entrants and established players; presently, majority of the gene switch platform developers are based in North America
§ In pursuit of gaining a competitive edge, gene switch developers are presently undertaking several initiatives to expand their existing capabilities and augment respective product portfolios
§ The growing interest in this domain is evident from the rise in licensing agreements over the last few years; majority of such deals were signed between players based in North America
§ Several investors, having realized the opportunity within this domain, have invested over USD 3.5 billion across various funding rounds in the past five years
§ Scientific articles being published for gene switch, reflect the growing research efforts of various industry and academic stakeholders; majority of the authors are affiliated to organizations based in North America
§ More than 360 patents have been filed / granted by various stakeholders in order to protect the intellectual property generated within this field since 2014
§ Based on historical trends, we expect a steady growth in the licensing of gene switch platforms, in order to meet the growing demand for safe and effective gene therapies
§ The gene switch market is expected to grow at a CAGR of 11.5% till 2035; the overall opportunity is anticipated to be well distributed across various segments, such as types of target therapies, application areas and key regions
Table of Contents
1.1. Introduction
1.2. Key Market Insights
1.3. Scope of the Report
1.4. Research Methodology
1.5. Key Questions Answered
1.6. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Emergence of Gene Switch
3.3. Applications of Gene Switch
3.4. Challenges Associated with Gene Switch
3.5. Concluding Remarks
4. MARKET LANDSCAPE
4.1. Chapter Overview
4.2. Gene Switch Platforms: Overall Market Landscape
4.3. Gene Switch Platform Developers: Developer Landscape
5. PRODUCT COMPETITIVENESS ANALYSIS
5.1. Chapter Overview
5.2. Assumptions and Key Parameters
5.3. Methodology
5.4. Product Competitiveness Analysis: Gene Switch Platforms
6. COMPANY PROFILES
6.1. Chapter Overview
6.2. aceRNA Technologies
6.2.1. Company Overview
6.2.2. Gene Switch Platform Portfolio
6.2.3. Recent Developments and Future Outlook
6.3. Autolus Therapeutics
6.4. Bellicum Pharmaceuticals
6.5. Cellectis
6.6. Kiromic BioPharma
6.7. panCELLa
6.8. Precigen
6.9. Sana Biotechnology
6.10. Sangamo Therapeutics
7. PARTNERSHIPS AND COLLABORATIONS
7.1. Chapter Overview
7.2. Partnership Models
7.3. Gene Switch Platforms: Partnerships and Collaborations
8. FUNDING AND INVESTMENT ANALYSIS
8.1. Chapter Overview
8.2. Type of Funding
8.3. Gene Switch Platforms: Funding and Investments Analysis
9. PUBLICATION ANALYSIS
9.1. Chapter Overview
9.2. Scope and Methodology
9.3. Gene Switch Platforms: Recent Publications
10. PATENT ANALYSIS
10.1. Chapter Overview
10.2. Scope and Methodology
10.3. Gene Switch Platforms: Patent Analysis
10.4. Gene Switch Platforms: Patent Benchmarking Analysis
10.5. Gene Switch Platforms: Patent Valuation
10.6. Leading Patents: Analysis by Number of Citations
11. BUSINESS MODEL ANALYSIS
11.1. Chapter Overview
11.2. Gene Switch Platform Developers: Business Model Analysis
11.3. Concluding Remarks
12. MARKET FORECAST AND OPPORTUNITY ANALYSIS
12.1. Chapter Overview
12.2. Key Assumptions and Forecast Methodology
12.3. Global Gene Switch Platform Market, 2023-2035
13. CONCLUDING REMARKS
14. APPENDIX 1: TABULATED DATA
15. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS
To view more details on this report, click on the link
https://www.rootsanalysis.com/reports/gene-switch-market.html
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